Wharton’s Jelly Injections for Knee Pain, Arthritis, Tendinitis & More

Regenerative medicine is a game-changing area of medicine with the potential to fully heal damaged tissues, offering solutions and hope for people who have conditions that were once thought to be beyond repair.
For many patients with debilitating knee osteoarthritis, treatment options are limited: steroid injections, joint replacement surgery, physical therapy, etc. At Axe Holistic Medicine, in Tampa, new cutting-edge treatment options like Wharton’s Jelly injections may be used to successfully treat patients with knee osteoarthritis, Achilles tendinitis, rotator cuff tendinitis, and degenerative arthritis.

While some people may have ethical issues with embryonic therapy, most everyone agrees that the use of Wharton’s Jelly injections raises no ethical or moral questions.

How Do Wharton’s Jelly Injections Work?

Wharton’s Jelly injections have the ability to develop — through a process called differentiation — into many different types of cells, such as cartilage, tendons, ligaments, etc. Wharton’s Jelly is a key component of regenerative medicine, as they open the door to new clinical applications.

Wharton’s Jelly treatment takes advantage of the body’s ability to repair itself. With Wharton’s Jelly injection therapy, our medical staff injects Wharton’s Jelly from amniotic tissues into your body. Wharton’s Jelly injections have anti-inflammatory properties, similar to cortisone and steroid shots. However, this type of therapy goes far beyond the benefits of standard “injection therapy.”

While cortisone and other drugs only provide temporary pain relief and over time can cause degeneration of soft tissues, Wharton’s Jelly injections actually restore degenerated tissue while providing pain relief. The growth factors in Wharton’s Jelly may replace damaged cells in your body. Additionally, injections contain hyaluronic acid, which lubricates joints and tendons, easing the pain and helping restore mobility.

What Benefits Does Wharton’s Jelly Injection Therapy Offer?


Wharton’s Jelly injections contain no steroids. Instead, the injections rely on naturally occurring anti-inflammatory agents, such as cytokines.


Wharton’s Jelly injections contain hyaluronic acid, which lubricates cartilage and promotes new cartilage growth.


Wharton’s Jelly injections contain growth factors, which stimulate tissue growth.


With Wharton’s Jelly injections, there is no threat of patient rejection.

Are Wharton’s Jelly Injections Safe?


Wharton’s Jelly injections are a preferred type of therapy because the cells come from an immunoprivileged site, which means that patient-rejection is extremely rare.


The use of Wharton’s Jelly injections are well researched, safe, and effective. 


All donors go through a rigorous screening process, as determined by the Food and Drug Administration (FDA) and American Association of Tissue Banks (AATB).

What Should I Expect with an Outpatient Therapy Procedure?

Initial Visit

An initial consultation with our medical team will be required to find out if you are a candidate for Wharton’s Jelly injections. If you are determined to be a candidate for Wharton’s Jelly injections your procedure will be scheduled for another day. This initial consultation is usually covered by your insurance plan.


For two weeks prior to your procedure, do not take aspirin or anti-inflammatory medications (NSAIDS).


Stand alone Wharton’s Jelly injections are done as an outpatient procedure, so most patients will leave the clinic and resume low impact activities the same day. Some patients have reported mild pain for 48-72 hours after their procedure, but this can often be attributed to the absence of their routine anti-inflammatory medications. After this time period, most patients will experience a gradual decrease in pain and some may begin to notice increased function.


To give your procedure the best chance to provide lasting results, our medical team recommends the following post-procedure restrictions:


Do not take anti-inflammatory medication for 2 weeks after your procedure.


Rest for the first 24-48 hours after your procedure.


Restrict the treated joint to low impact / general use for the first 2 weeks.


For weeks 3-4, you may resume walking, cardio, and light lifting.


After 4 weeks, you may resume running and weightlifting.


Pay special attention to the treated joint and contact your physician with any questions or concerns you may have.

Please Note:

If you are having Wharton’s Jelly injections procedure in conjunction with another surgical procedure, your recommendations may change. Consult with your physician on the guidelines and restrictions for your specific case.

Are Wharton’s Jelly Injections Covered By My Insurance?

No. Because injections are considered investigational for orthopedic applications, most insurance companies will not cover the cost. Please contact our office to discuss cash payment options.

Am I a Candidate for Wharton’s Jelly Injection Therapy?

Patients suffering from any kind of joint, tendon, or ligament pain may be considered as candidates for Wharton’s Jelly injections at Axe Holistic Medicine. In some cases, patients with severe degenerative osteoarthritis may not be eligible for Wharton’s Jelly injections.

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*Results are not guaranteed and the results depicted on this site may or may not be typical. Results will vary based on each patient’s physical health, family history, diet and exercise, physical condition and adherence to the Program. See our refund policy.

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